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Autoimmune Liver Disease

Chairpersons - Nihar Mohapatra, Rahul Jain, Rajanikanth Patcha

🗓️ 22 Nov 2025 🕒 10:40 - 11:25 📍Hall C

Theme - When friend beomes foe: The art of reconciliation

Objectives -

Learn T-cell role – Understand how T-cell changes drive PBC, AIH, and overlap syndromes.

Diagnose overlap – Use current scores and AI tools to identify PBC-AIH overlap.

Manage refractory disease – Plan treatment for tough cases, control pruritus, and know when to consider liver transplant.

T cell immunology

10:40 - 10:46 Introductory Talk

Speaker: Kaushal Madan

Case based Panel Discussion: 39 yr old female diagnosed as PBC and intractable pruritus, LFTs shows ALT 880IU/ ml

Sub-topics:
1. Differentials for High ALT levels in PBC patient.
2. Diagnosis of overlap syndrome? Newer scoring system.
3. Role of AI in diagnsosis of PBC-AIH.
4. Prognosis in comparison to AIH alone.
5. Management strategy in this patient (including pruritus), Role of Liver Transplantation

10:46 - 11:11 Case based panel discussion

Moderator : Praveen Sharma

Panelists: B C Sharma, Babu Lal Meena, Mithra Prasad, Puneet Dargan, Saurabh Argal

Management of refractory AIH and overlap syndrome: Role of medical management vs Liver transplant

11:11 - 11:21 Talk ( Evidence Based Review)

Speaker: Vivek A Saraswat

Moderated Q&A

11:21 - 11:25

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