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Outliers: Obese recipient with metabolic syndrome / Pediatric Recipients (45mins)

Chairpersons - Achirabha, Dileep Rana, Nita George, Rishabh Jain, Sachin Anand

🗓️ 22 Nov 2025 🕒 9:00 - 9:45 📍Hall B

Theme - Not a statistical outlier: challenges of the mainstream

Objectives -

Understanding the implications of anesthesia issues in the backdrop of obesity 2. To optimize transition to sucessful transplant in Pead ALF

Metabolic syndrome and autonomic dysfunction: Challenge for anesthesiologists in recipient operation

9:00 - 9:10 Didactic Talk

Speaker: Sanjeev Aneja

Debate: LDLT can be done safely with BMI > 40

9:10 - 9:30 Debate

Moderator : Ilankumaran Kaliamoorthy

Debate: LDLT can be done safely with BMI > 40

Pros

9:10 - 9:18 Debate

Speaker: Sumit Goyal

Debate: LDLT can be done safely with BMI > 40

Cons

9:18 - 9:26 Debate

Speaker: Manjunath Balasubramaniam

9:26 - 9:30 Rebuttal & Discussion

Bridging the gap from neuroprotection to transplant in Pediatric ALF

9:30 - 9:40 Didactic Talk

Speaker: Maninder Dhaliwal

9:40 - 9:45 Moderated Q&A

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Metabolic & Genetic liver diseases

Chairpersons - Akanand Singh, Harikumar Nair, Nalini Bansal, Sukrit Singh

🗓️ 22 Nov 2025 🕒 09:40 - 10:40 📍Hall C

Theme - Current status of role of genetic testing in Cholestatic disorders and cryptogenic cirrhosis

Objectives -

Understand genetic testing – Know when to use genome sequencing in cryptogenic cirrhosis and cholestatic liver disease.

Evaluate high transaminases – Identify possible causes like infection, autoimmunity, or drugs in stable cirrhosis.

Plan diagnostic work-up – Learn a stepwise approach, including biopsy, for unexplained liver disease.

Debate: All cryptogenic cirrhosis should undergo genome sequencing

09:40 - 09:47 Debate- For

Speaker: Amit Goel

Debate: All cryptogenic cirrhosis should undergo genome sequencing

09:47 - 09:54 Debate- Against

Speaker: Swapnil Dhampalwar

Debate: All cryptogenic cirrhosis should undergo genome sequencing

Quick Rebuttal & Discussion with Moderator

09:54 - 09:57 Debate

Role of genetic testing in cholestatic disorders of adults

09:57 - 10:05 Didactic talk

Speaker: Seema Alam

Case based Panel Discussion: 30 yr male with child A cirrhosis have AST and ALT of 600IU/550 IU /ml

Sub-topics:
1. What are the most likely causes of such high transaminase levels in a patient with known Child-Pugh A cirrhosis?
2. Are there any infectious or autoimmune etiologies that need to be considered and investigated further?
3. Herbal supplements, or other drugs leading to this scenario?
4. Work up for cryptogenic cirrhosis
5. Role of Liver Biopsy in this patient
6. Algorithm for work up

10:05 - 10:30 Case Based Panel Discussion

Moderator : Harshad Devarbhavi

Panelists: Amitava Goswami, Lovkesh Anand, Vinod Arora, Monika Jain

Moderated Q&A

10:30 - 10:40

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