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PALF : Liver Transplant in Pediatric Acute Liver Failure

Chairpersons - Aathira Ravindranath, Sufla Saxena, Swati Bhardwaj

🗓️ 22 Nov 2025 🕒 12:25 - 13:25 📍Hall C

Theme - Scoring Systems, Prognostic Models, and Perioperative Challenges

Objectives -

1. Understand the role of scoring systems and prognostic models in timely decision-making for LT in pediatric ALF
2. Review a case journey from ALF diagnosis to LT and postoperative care
3. Decide critical issues in timing and candidate selection for transplant in ALF
4. Learn about perioperative hemodynamic monitoring and critical care in PALF
5. Discuss novel therapies and evolving strategies in PALF management

Prognostic Modeling in PALF: Diagnostic criteria and efficient use of scoring systems (e.g., King’s College, Clichy, Liver Injury Units, PALF-specific models, NWI) to guide transplant decisions

12:25 - 12:35 Talk

Speaker: Seema Alam

Case Discussion: From ALF to LT: case-based walk-through of decision-making, transplant timing, and postoperative care

12:35 - 12:50 Case Based Panel

Moderator : Smita Malhotra

Panelists: Aditya Nanavati, Chandrika Bhat, Nidhi Rawal, Ravi Raya, Sachin Anand

Bridging Therapies: Plasma exchange, CRRT, MARS, and other extracorporeal support systems in PALF

12:50 - 13:00 Talk

Speaker: Rachna Sharma

Perioperative Hemodynamic Monitoring: Hemodynamic instability in ALF:- Invasive vs non-invasive monitoring, fluid balance, vasopressor use, and ICU strategies

13:00 - 13:10 Talk

Speaker: Nameet Jerath

Emerging Therapies: Novel immunomodulatory and hepatoprotective strategies; gene-targeted approaches in select etiologies

13:10 - 13:20 Talk

Speaker: Nedim Hadzic

Moderated Q&A

13:20 - 13:25

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